Blepharospasm is a debilitating disorder of involuntary spasms of the eyelid muscles. The onset of blepharospasm is typically in the fifth to sixth decade and is more common in women. The cause of blepharospasm is not known. It is often made worse by stress, fatigue, bright lights, watching television or driving, and social interactions. Systemic medications have limited use in treating the disease. Botox treatments can be life changing for these patients.